What Causes Cognitive Changes

It is estimated that 3 out of 4 cancer patients experience cognitive changes during treatment. The condition is also referred to as chemo brain since it is most commonly associated with chemotherapy, but can also be associated with hormone therapy, radiation, and surgery. These treatments may cause long-term, short-term, or delayed mental changes or cognitive problems. This may make it hard to remember certain things, finish tasks, concentrate, or learn new skills.

What are the signs and symptoms of cognitive changes?

  • Memory loss 
  • Difficulty thinking of the right word for a particular object
  • Difficulty following the flow of a conversation
  • Trouble concentrating or focusing on one thing
  • Difficulty doing more than one thing at a time 
  • More difficulty doing things you used to do easily
  • Fatigue
  • Confusion
  • Mental fogginess

Do cognitive difficulties ever go away?

It has been documented that cancer patients experience these symptoms when they are depressed. According to research conducted in the past decade, cancer patients may experience cognitive impairment due to either brain damage caused by their tumour or treatment. Recently, chemotherapy has been discovered to cause cognitive difficulties, despite radiation causing cognitive difficulties for decades.

Generally, people experience mental changes for a short period of time. Others may experience mental changes that are long-lasting or delayed. It is possible for the intensity of these symptoms  to vary from one patient to another, as well as when and how long they last. Often, the changes you notice are subtle and may even be unnoticed by others.

There is no universal cure for cognitive changes, but some symptoms may fade after treatment is over. In some cases, it may take up to a year for patients to feel normal again after treatment. In spite of the fact that chemo brain has no known cause, certain factors may increase its likelihood of occurring or make it more severe. 

Is there anything that can increase cognitive changes?

These factors below may increase your risk of cognitive changes 

  • Older age
  • High - dose treatment 
  • Chemotherapy agent combinations
  • Additional treatments, such as hormone therapy or radiation
  • Other medical conditions 
  • Treatment to the brain, such as chemotherapy into the fluid around the spinal cord (intrathecal chemotherapy) or radiotherapy to the brain
  • A genetic variation that might make some people more likely to develop chemo brain.

Discover techniques and tips on how to reduce cognitive changes below.

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